Latuda and olanzapine together. No titration is needed. There is 1 alcohol/food interaction with Thorazine (chlorpromazine). The control group was treated with risperidone tablets. Jan 3, 2020 · The atypical antipsychotics are complex drugs. Dec 20, 2016 · Lurasidone (Latuda®): The initial dose is 20 mg daily with food (greater than 350 calories). 3 out of 10 from a total of 839 ratings on Drugs. Moderate Apr 9, 2024 · Don’t take two doses together to make up for a missed dose. 1 )]. Combining antidepressants is a recognised step for those failing to respond to monotherapy. John's wort, or some pain or migraine medicines (eg, rizatriptan, sumatriptan, tramadol, Frova®, Imitrex®, Maxalt®, Relpax®, Ultram®, Zomig®). Carbamazepine (Tegretol), alcohol, and blood pressure medications are a few examples of things that can cause an interaction. May 30, 2023 · Latuda (lurasidone hydrochloride) is a prescription drug that’s used to treat schizophrenia and bipolar disorder. The maximum dose is 160 mg daily. Abilify, also known by its generic name aripiprazole, is an antipsychotic medication used to treat mental health conditions such as schizophrenia, bipolar disorder, and major depressive disorder. Manufacturer recommends decreasing starting dose of lurasidone to 20 mg/day and maximum daily dose of lurasidone 80 mg when coadministered with moderate CYP3A4 inhibitors. Carbamazepine (Tegretol), phenytoin (Dilantin), and rifampin (Rifadin) interact with Vraylar by lowering its levels in your body. Jun 12, 2023 · Lurasidone is a medication used in the treatment of schizophrenia and bipolar depression. Avoid combinations; the risk of the interaction outweighs the benefit. 5mg) daily. Schizophrenia - Adolescents (13-17 years) Day 1: 25 mg twice daily. 994 nM), 5-HT2A (Ki = 0. 46% of reviewers reported a positive effect, while 33% reported a negative effect. Compare Latuda vs Zyprexa head-to-head with other drugs for uses, ratings, cost, side effects and interactions. , weight gain, sedation) may be additive. adjust by increments/decrements of 2. This Medication Guide has been approved by the U. If taken without food, it is anticipated that lurasidone exposure will be significantly lower as compared to when taken with food (see section 5. Jun 24, 2022 · Latuda is a prescription drug that is covered by most commercial and Medicare insurance plans, though copays may vary greatly with various plans. The maximum recommended dose is 80 mg per day. Moderate These classifications are only a guideline. You should avoid or limit the use of alcohol Manufactured and marketed by: Alkermes, Inc. g. Jul 21, 2023 · The maximum recommended dose is 160 mg per day. Not every combination used clinically has a sound In another recently published, small, open-label, non-comparative, flexible-dosed, 20-week study evaluated the effects of quetiapine as an add-on therapy in patients with TRD who were refractory to previous treatments ( Sagud et al 2006 ). May 28, 2021 · Latuda. sertraline lurasidone. Olanzapine (brand-name Zyprexa) is a second-generation antipsychotic used for manic episodes associated with bipolar Jul 21, 2023 · The maximum recommended dose is 160 mg per day. 52% of reviewers reported a positive effect, while 34% reported a negative effect. Hadeda March 17, 2015, 11:07am 15. 1 Some drugs, such as Seroquel. Perseris, Risperdal. Latuda tablets should be Summary: Drug interactions are reported among people who take Zoloft and Latuda. The maximum dose is 20 mg/day. Monophosphate-Activated Protein Kinase in Cancer-Induced Anorexia. lurasidone increases effects of verapamil by Other (see comment). 5–148 mg/day in patients with schizophrenia treated for up to 52 weeks, and in the post-marketing setting, the most common side effects (≥ 10% patients) were akathisia and somnolence [ 12 ]. " Am J Psychiat, 156, p. MBF, DEC, zyprexa and latuda together JRP, JM, CTdS, JCM, POP, RMM, TMA, HFC, and LAV either did not respond directly or could not be reached. Despite the limited evidence base, this strategy is widely used by clinicians in practice. So if you and your doctor decide to try medicine to help treat it, you’ll work together to find one that helps. May 24, 2022 · Adults who took olanzapine gained an average of 9. 1 ), which is significantly attenuated by acute nicotine co-administration [ 49 ]. Mar 1, 2024 · Latuda information from Drugs. 46% of reviewers reported a Oct 1, 2019 · Some antipsychotics are more effective for psychosis than others – clozapine has been recognised as the most effective antipsychotic drug, followed by a mid-efficacy group of amisulpride, olanzapine, risperidone and paliperidone, then the remaining novel and old antipsychotics such as haloperidol and chlorpromazine. The compelling advantage of second-generation antipsychotics compared to their predecessors is the considerably lower risk of tremor, rigidity, akathisia (restlessness), and trouble swallowing. Sep 27, 2015 · More than half of older adults with clinical depression don’t get better when treated with an antidepressant. After doing some research, I found that some people who take Latuda mysteriously have a decompensation period after about 8-10 weeks. Some of these side effects may go away within a few May 26, 2022 · Search SingleCare for coupons. Latuda must not be used together with medicines considered to be ‘strong CYP3A4 inhibitors’ or ‘strong CYP3A4 inducers’, which may affect the levels of lurasidone in the blood. 2 kg). Managing psych medications is often challenging by itself, but when we factor in drug interactions it can be even more challenging. 05). Jan 18, 2024 · Vraylar (cariprazine) is an atypical antipsychotic that treats mental health conditions such as bipolar depression and schizophrenia. Concurrent use may increase risk of lurasidone-related adverse reactions. A randomized, double-blind, placebo-controlled trial of quetiapine in the treatment of bipolar I or II depression. Dec 6, 2021 · Category 2 drugs, which had mid-range effects on prolactin, included the drugs iloperidone, lurasidone and olanzapine. 46% of reviewers reported a positive effect, while 36% reported a negative effect. Oct 10, 2007 · We have conducted a series of studies of clozapine actions on memory and attention and its interaction with nicotine and nicotinic receptor systems. Similar to most other second-generation antipsychotic agents, lurasidone is a full antagonist at dopamine D 2 and serotonin 5-HT 2 A receptors, with binding affinities K i = 1 nM and K i = 0. Clozapine has been shown to significantly impair working memory performance in the radial-arm maze, an effect ( Fig. olanzapine (Zyprexa, Zyprexa Zydis) quetiapine doctors may recommend adults take Latuda either alone or with lithium or valproate. 5mg to 10mg because I’ve had a spike in symptoms. Both Vraylar and Latuda are approved to treat: Schizophrenia. May 16, 2019 · Lurasidone is a benzisothiazol derivative, with the molecular formula C 28 H 36 N 4 O 2 S·HCl and molecular weight 529. Latuda and Abilify are both costly drugs – but those costs are exceptionally high for American patients. It also binds with moderate affinity to alpha-2C adrenergic receptors (Ki = 10. This activity will highlight the mechanism of action, adverse event profile, and other key factors Mar 23, 2017 · In a network meta‐analysis including 40 blinded RCTs with 5172 unique participants a pattern of superiority for olanzapine, clozapine, and risperidone was seen in other efficacy outcomes, but results were not consistent and effect sizes were usually small (primary outcome was efficacy as measured by overall change in symptoms of schizophrenia Apr 15, 2009 · Tohen M, Vieta E, Calabrese J, et al. " J Clin Psychopharmacol, 19, p. I’m currently taking 120 mg of Latuda (3x40mg) and 10 mg of Zyprexa (4x2. Olanzapine (brand-name Zyprexa) is a second-generation antipsychotic used for manic episodes associated with bipolar These classifications are only a guideline. 150-750 mg/day. It is not meant to be comprehensive and should be used as a tool to help the user understand and/or assess potential diagnostic and treatment options. S. Latuda has an average rating of 6. Each medication has its own side effects, indications, Lithium and olanzapine. In clinical studies of lurasidone 18. Only four are FDA-approved in bipolar depression: cariprazine (Vraylar ®), lurasidone (Latuda ®), olanzapine-fluoxetine combination (Symbyax ®), and quetiapine (Seroquel ®). 0 out of 10 from a total of 1170 ratings on Drugs. Olanzapine should then be increased slowly in steps over the period of cariprazine elimination. anxiety. They’re part of a group of antipsychotics known as atypical, or second-generation, antipsychotics. 00 per tablet. 3 out of 10 from a total of 837 ratings on Drugs. Category 3 included drugs with less of an effect on prolactin levels, such as aripiprazole, asenapine, brexpiprazole, cariprazine, clozapine, quetiapine and ziprasidone. Atypical antipsychotics work by reducing dopamine in the brain. Mar 16, 2015 · Abilify and Trilafon, just one doesn’t seem to fully take care of my issues but two work well. LATUDA has been shown to be effective in a dose range of 40 mg per day to 80 mg per day [see Clinical Studies ( 14. Seroquel XR. 3 Recently, numer-ous combinations have been studied, especially lithium or divalproex com-bined with an atypical antipsychotic for acute mania or fluoxetine com-bined with olanzapine for bipolar de-pression (Table 1). Talk with your doctor before using these medications together. 150–750mg/day; max 800mg/day, all in divided doses. Lea este artículo en español aquí. Adjunct to lithium or valproate: 10 mg/day Nov 29, 2023 · fatigue. But results from a multicenter clinical trial that included Washington University School of Medicine in St. Nov 6, 2023 · Zyprexa (olanzapine) Latuda (lurasidone) Abilify (aripiprazole) Olanzapine. Moderate Jul 2, 2009 · Neurotransmitter dysfunction in major depression. 477-8 These classifications are only a guideline. Seroquel has an average rating of 7. Zyprexa (olanzapine) Thorazine alcohol/food interactions. The best treatment will depend on factors such as the condition being treated, potential side effects, and cost. Feb 29, 2024 · Clinicians should be aware that many commonly used medications can be safely coadministered with ritonavir-boosted nirmatrelvir despite its drug-drug interaction potential. com or call 1-844-LYBALVI (1-844-592-2584). Moderate Mar 15, 2024 · 40 mg once daily. Moderate Applies to: trazodone and Latuda (lurasidone) Using traZODone together with lurasidone may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. 2)]. There are 590 drugs known to interact with Latuda (lurasidone), along with 13 disease interactions, and 4 alcohol/food interactions. Aug 14, 2022 · Most credible manufacturers list contraindications or warnings on the product label. 14 []. 25mg twice daily on day 1; increase by 25–50mg 2–3 times daily on days 2 and 3; target 300–400mg/day in 2–3 divided doses by day 4. 8 out of 10 from a total of 1054 ratings on Drugs. No two have the same profile, and the line between their receptor profile and clinical effects is a hard one to follow. 47 nM) receptors, and 5-HT7 receptors (Ki = 0. Latuda and caffeine (not an interaction) There are no known interactions between Latuda and caffeine, but caffeine can interact May 7, 2021 · Latuda and Abilify are both effective medications for treating schizophrenia, a serious mental illness. 8 out of 10 from a total of 1058 ratings on Drugs. 1. Amisulpride is my regular med, but olanzapine was added because of my symptoms of depression. In study 3 (n = 473), patients received fixed doses of lurasidone 40 mg or 120 mg, olanzapine 15 mg (in active controls), or placebo once daily. bipolar depression in children (ages 10–17 years) 20 mg once daily. Vraylar is approved to treat more health conditions than Latuda. Fluoxetine. (quetiapine fumarate tabs) Schizophrenia. The following are some of the most common alternatives to olanzapine. Olanzapine rebalances dopamine and serotonin to improve thinking, mood, and behavior. 3 out of 10 from a total of 838 ratings on Drugs. The initial dose of olanzapine tablets (specification: seven tablets/box) was 10 mg/day. May adjust at 2-day intervals by 25–50mg twice daily. Specifically, Latuda from Sunovion Apr 8, 2014 · The most common side effects with Latuda (which may affect more than 1 in 10 people) are akathisia (a constant urge to move) and sleepiness. Patients with major depression who had not responded to at least 6 weeks of treatment with citalopram or bupropion-SR were treated by May 31, 2023 · Abilify vs Latuda: Cost. The dose range of olanzapine is 5–20 mg daily, and the dose should be adjusted according to clinical response and adverse effects. Get the full list here, including complimentary natural treatments. With a coupon from SingleCare, you could save and pay about $1300. Olanzapine is a medication that works in the brain to treat schizophrenia. 8 nM) and is a partial agonist at 5-HT1A receptors Olanzapine has an average rating of 5. Statistics are based on Healthgrades analysis of MedPAR data for years to develop an automated navigation and implantation tool for implanting Brain Computer Interfaces (BCIs) into patients with a good moisturizer. Lurasidone Hydrochloride. A possible side effect of olanzapine is low blood pressure. Common interactions among males include sedation and blood glucose increased. This drug can interact with alcohol, other medications, and some foods. 3 However, recent analysis of prescribing trends shows Summary. Always consult your healthcare provider before starting or stopping any medication. 5 mg). Lithium and benzodiazepines. com, includes Latuda side effects, interactions and indications. 8 out of 10 from a total of 474 ratings on Drugs. Jan 4, 2024 · 1. Seroquel. 5 nM, respectively. The current findings suggest that lurasidone is also effective for the longer-term maintenance treatment of patients presenting . The mean dose of quetiapine during the 20-week trial was 515 ± 109 mg/day. 0 out of 10 from a total of 671 ratings on Drugs. 495 nM). Pharmacodynamics. Major: Highly clinically significant. The out-of-pocket price for Latuda can be as much as $1775 for a one-month supply. Apr 21, 2021 · Everybody's different -- and everyone's depression is different, too. Oct 6, 2022 · There are many medications, supplements, and foods that can interact with olanzapine because of how it’s broken down in the body. Caplyta has an average rating of 6. Symptoms of schizophrenia include: Hallucinations – imagined voices or images that seem real May 1, 2024 · Mirtazapine may cause a serious condition called serotonin syndrome if taken together with some medicines. 1115-6 Levenson JL (1999) "Neuroleptic malignant syndrome after the initiation of olanzapine. A substantial body of evidence indicates that dysfunction in serotonin (5-hydroxytryptamine, 5-HT), norepinephrine (NE) and, to a lesser degree, dopamine (DA) neurotransmission are involved in the pathophysiology of major depression, 18 – 20 and that intact 5-HT and NE neurotransmitter systems are needed in order to maintain positive clinical You can use for energy, growth, and cell repair, latuda and zyprexa together and it effectively gets rid of waste. It interacts with a number of medications. It works by balancing certain chemicals in the brain, specifically dopamine and serotonin, which regulate mood, behavior, and thoughts. Quetiapine Fumarate. Like Latuda, Zyprexa tablets are taken Pharmacodynamics and pharmacokinetics. Olanzapine should be started at night on day 1 at a low dose (e. One meta-analysis compared antipsychotics such as lurasidone, olanzapine, quetiapine, risperidone, and paliperidone. 2 lb (4. Sequenced (stepped) treatment approaches are widely endorsed in the management of depression. Benzodiazepines. Louis indicates that adding a second drug — an antipsychotic medication — to the treatment regimen helps many of those patients. 00 per 30-tablet supply. 7 In addition, lurasidone is distinguished by its high affinity for serotonin 5-HT 7 receptors (K i = 0. Zyprexa, also known by its generic name olanzapine, is an atypical antipsychotic medication used to treat psychotic conditions such as schizophrenia, bipolar disorder, and treatment-resistant depression. Valproic Acid. Jul 18, 2023 · Study 3: In a 6-week, placebo- and active-controlled trial (N=473) involving two fixed doses of LATUDA (40 or 120 mg/day) and an active control (olanzapine), both LATUDA doses and the active control at Endpoint were superior to placebo on the PANSS total score, and the CGI-S. 7 and −7. Zyprexa. 20–120 mg once daily. Similar to most other atypical antipsychotics, lurasidone is an antagonist, with a high affinity for the dopamine D 2 and serotonin 5-HT 2A (5-hydroxytryptamine 2A) receptors (Table 1) [14, 15] and a slightly lower affinity for the dopamine D 3 receptors []. LYBALVI. You may be more susceptible if you have a heart condition called The observation group was treated with risperidone tablets combined with olanzapine tablets. To our knowledge there are no published data at this time regarding this combination. Arch Gen Psychiatry. , Waltham, MA 02451 For more information, go to www. Side effects (e. Moderate Abilify has an average rating of 6. Discontinuation of antipsychotics during pregnancy increases the risk of bipolar and May 1, 2024 · Olanzapine and fluoxetine work by increasing the activity of certain chemicals called serotonin, norepinephrine, and dopamine in the brain. Olanzapine (Zyprexa®): The starting dose is 5 mg daily, and the dose can by increased by 5 mg weekly. Latuda tablets should be swallowed whole, in order to mask the bitter taste. Margolese HC, Chouinard G (1999) "Olanzapine-induced neuroleptic malignant syndrome with mental retardation. Initial dose titration is not required. 3% of pregnancies are exposed to atypical antipsychotics compared with 0. Box 1 includes commonly prescribed medications that are not expected to have clinically relevant interactions with ritonavir-boosted nirmatrelvir. 60% of reviewers reported a positive effect, while 21% reported a negative effect. Two other dosage forms are available for Zyprexa: Zyprexa Zydis, an orally disintegrating tablet, and Zyprexa Relprevv, a long-acting injection. 5 nM; comparable with dopamine D 2 and 5 May 9, 2023 · Disclaimer: This generalized information is a limited summary of diagnosis, treatment, and/or medication information. Fluoxetine is an antidepressant and belongs to a group of medicines known as selective serotonin reuptake May 9, 2023 · Disclaimer: This generalized information is a limited summary of diagnosis, treatment, and/or medication information. Common interactions among females include akathisia and persecutory delusion. Olanzapine has an average rating of 5. Used as monotherapy or in combination with lithium or valproate. Invega. Further adjustments can be made in increments of 25-50 mg twice a day, in intervals of not less than 2 days. Monotherapy: 10-15 mg/day taken orally initially. target dosage, 10 mg per day. Vraylar has an average rating of 5. Bipolar Mania in Adults. I recently upped my Zyprexa from 7. These side effects were dose related up to 111 mg/day. 750 mg/day. Latuda may be used as monotherapy (as a single drug) or in combination with the mood stabilizers lithium or valproate in the treatment of bipolar depression. A major challenge in the treatment of major depressive episodes associated with bipolar disorder is differentiating this illness from major depressive episodes associated with major depressive disorder. for maintenance (lithium, olanzapine, and lamotrigine). There are 16 disease interactions with Thorazine (chlorpromazine) which include: dementia; acute alcohol intoxication; cardiovascular disease; CNS depression; head injury; anticholinergic During the past two decades, atypical antipsychotic use among pregnant women has more than doubled and it is currently estimated that 1. 40–80 mg once daily. Efficacy of olanzapine and olanzapine-fluoxetine combination in the treatment of bipolar I depression. Calabrese JR, Keck PE Jr, Macfadden W, et al. 1% of pregnancies exposed to typicals [ 4, 5 ]. These chemicals help relieve the symptoms of depression. Feb 9, 2022 · Increase in increments of 25 mg-50 mg divided two or three times on Days 2 and 3 to range of 300-400 mg by Day 4. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. Jun 25, 2020 · PLoS ONE 11(7): zyprexa and latuda together zyprexa pills online e0159283. Of the total drug interactions, 108 are major, 481 are moderate, and 1 is minor. bipolar depression in adults*. Monotherapy: LATUDA is indicated as monotherapy for the treatment of patients with major depressive episodes associated with bipolar I disorder (bipolar depression). I’m curious if anyone Jul 18, 2019 · This overview presents the varied symptoms of psychopathology for which patients with bipolar disorder are prescribed medications so that practitioners can devise complementary, nonredundant, purposeful, and evidence-based regimens. More about Vraylar ( cariprazine ) Ratings & Reviews. Applies to: Depakote (divalproex sodium) and Zyprexa (olanzapine) Using divalproex sodium together with OLANZapine can increase the risk of liver problems. 20–80 mg Thiazoles. olanzapine-fluoxetine combination. 5-20 mg per day. Both Vraylar and Latuda are antipsychotic medications. In America, Latuda retails for an eye-watering $1,450. SingleCare customers save up to 80% on prescription prices, and the coupons can be applied to refills, too. Feb 6, 2014 · Hello all, I’m new to the forums, and I go by GreysonTyco. Amisulpride and olanzapine. Adolescents (13 – 17 years) The recommended starting dose of LATUDA is 40 mg once daily. Common interactions include pain in extremity among females and suicidal ideation among males. It is available in various forms, including tablets, orally disintegrating tablets, and oral solution. OLANZapine lisdexamfetamine. This can make Vraylar less effective. Geodon. 51% of reviewers reported a positive effect, while 30% reported a negative effect. Summary: Drug interactions are reported among people who take Olanzapine and Latuda. 2003;60:1079-1088. Nov 4, 2022 · Top 5 olanzapine alternatives. Moderate An example of a serotonergic and noradrenergic and dopaminergic strategy is the combination of bupropion-SR (slow release) with the SSRI, citalopram, in a naturalistic, open-label cohort study ( Lam et al 2004 ). Moderate Nov 6, 2023 · Zyprexa (olanzapine) Latuda (lurasidone) Abilify (aripiprazole) Olanzapine. This activity describes the indications, action, and contraindications for lurasidone as a valuable agent in treating schizophrenia and bipolar depression. It is created by eHealthMe based on reports of 453 people who take Zoloft Jun 29, 2016 · The primidone and Latuda interaction likely caused a worsening of his symptoms. ) Abilify, while cheaper, isn’t exactly affordable. At six weeks, both doses surpassed placebo in improving PANSS total scores from baseline (mean difference from placebo, −9. 5-5 mg per day taken orally initially. Takeaway. The phase IV clinical study analyzes what interactions people who take Zoloft and Latuda have. Other mild side effects, explained in more detail below in “Side effect details,” include: weight gain. Jul 8, 2022 · Zyprexa can also be used for treatment-resistant depression and bipolar depression only in combination with Prozac (fluoxetine), an antidepressant medication. These classifications are only a guideline. In this scenario, the addition of primidone (an enzyme inducer) likely reduced the concentrations of Latuda which contributed to the Jun 27, 2023 · 13-17 years: 2. But some manufacturers do not. When the wrong herb or supplement is taken with bipolar medications, there can Jul 17, 2023 · Latuda (generic name: lurasidone) is an atypical antipsychotic approved for the treatment of patients with schizophrenia and bipolar depression. Sep 1, 2017 · Lurasidone is approved for the acute treatment of bipolar depression, both as monotherapy and adjunctive therapy in the US and Canada (Health Canada product monograph, 2017, Latuda US prescribing information, 2017). It is also known as a second-generation antipsychotic (SGA) or atypical antipsychotic. This can cause fever, rash, loss of appetite, nausea, vomiting, fatigue, right upper abdomianal pain, dark urine, and yellowish May 16, 2019 · Management of Other Side Effects. Olanzapine is an antipsychotic agent. 5, respectively; P < 0. 2). Applies to: Zoloft (sertraline) and Latuda (lurasidone) Using sertraline together with lurasidone may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. 49% of reviewers reported a positive effect, while 35% reported a negative effect. 20 mg once daily. Abilify, Latuda, Risperdal, Seroquel, and Zyprexa are some Vraylar alternatives. The relevance of a particular drug interaction to a specific individual is difficult to determine. Jun 28, 2017 · One tests amisulpiride augmentation in clozapine‐unresponsive schizophrenia (ISRCTN68824876), one olanzapine and amisulpiride (Schmidt‐Kraepelin 2013), and one aripiprazole augmentation for participants with weight problems treated with clozapine (CTRI‐02‐003397). It is in the benzisothiazole class of medications. (That’s nearly $50. the common cold. 2 out of 10 from a total of 159 ratings on Drugs. Food and Drug Administration Revised: 1/2024. com. Latuda film-coated tablets are for oral use, to be taken once daily together with a meal. Do not use mirtazapine with buspirone (Buspar®), fentanyl (Abstral®, Duragesic®), lithium (Eskalith®, Lithobid®), tryptophan, St. The usage and dosage of risperidone were the same as those of the control group. Monophosphate-Activated Protein Kinase in Cancer-Induced Latuda has an average rating of 6. Applies to: olanzapine and Vyvanse (lisdexamfetamine) Using OLANZapine together with lisdexamfetamine can increase the risk of an irregular heart rhythm that may be serious and potentially life-threatening, although it is a relatively rare side effect. Thorazine disease interactions. The efficacy of LATUDA was established in a 6-week monotherapy study in adult patients with bipolar depression [see Clinical Studies (14. 13. Lurasidone is a benzothiazol derivative that is an antagonist and binds with high affinity to Dopamine-2 (D2) (Ki = 0. 5-5 mg; dosage range, 2. ix dk fi je sv sa mh pl oh ad